Protein Name: WD repeat-containing protein 82
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UniprotKB/SwissProt ID: WDR82_HUMAN (Q6UXN9)
Gene Name: WDR82
Synonyms: TMEM113, WDR82A
Organism: Homo sapiens (Human).
Function: Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Note=Associates with chromatin.
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Graphical Visualization of Ubiquitination Sites:
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| Overview of Protein Ubiquitination Sites with Functional and Structural Information |  |
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