Protein Name: WD repeat and SOCS box-containing protein 1
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UniprotKB/SwissProt ID: WSB1_HUMAN (Q9Y6I7)
Gene Name: WSB1
Synonyms: SWIP1
Organism: Homo sapiens (Human).
Function: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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Graphical Visualization of Ubiquitination Sites:
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Overview of Protein Ubiquitination Sites with Functional and Structural Information | |
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