Protein Name: E3 ubiquitin-protein ligase ZFP91
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UniprotKB/SwissProt ID: ZFP91_HUMAN (Q96JP5)
Gene Name: ZFP91
Synonyms: ZNF757
Organism: Homo sapiens (Human).
Function: Atypical E3 ubiquitin-protein ligase that mediates 'Lys- 63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non- canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.
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Graphical Visualization of Ubiquitination Sites:
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| Overview of Protein Ubiquitination Sites with Functional and Structural Information |  |
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