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Protein Name: E3 ubiquitin-protein ligase ZNRF2

UniprotKB/SwissProt ID: ZNRF2_HUMAN (Q8NHG8)

Gene Name: ZNRF2

Synonyms: RNF202

Organism: Homo sapiens (Human).

Function: May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein. Cell junction, synapse, presynaptic cell membrane; Peripheral membrane protein. Note=Present in presynaptic plasma membranes in neurons.

Graphical Visualization of Ubiquitination Sites:
Overview of Protein Ubiquitination Sites with Functional and Structural Information
InterPro ID Domain
IPR001841
IPR013083