Protein Name: Eukaryotic translation initiation factor 4E-binding protein 1
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UniprotKB/SwissProt ID: 4EBP1_HUMAN (Q13541)
Gene Name: EIF4EBP1
Organism: Homo sapiens (Human).
Function: Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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Overview of Protein S-nitrosylation Sites with Functional and Structural Information | |
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