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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Aspartate aminotransferase, mitochondrial

UniprotKB/SwissProt ID: AATM_RAT (P00507)

Gene Name: Got2

Synonyms: Maat

Organism: Rattus norvegicus (Rat).

Function: Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix. Cell membrane. Note=Located in the mitochondria of liver, pancreas, spleen, heart, pituitary gland and submandibular gland cells. In kidney, located in the mitochondria, on the cell surface of regions with protrusions in distal tubu

Network with metabolic pathway:
Kegg map ID Pathway Link
map00250"Alanine, aspartate and glutamate metabolism"
map00270Cysteine and methionine metabolism
map00330Arginine and proline metabolism
map00350Tyrosine metabolism
map00360Phenylalanine metabolism
map00400"Phenylalanine, tyrosine and tryptophan biosynthesis"
map04975Fat digestion and absorption
map012102-Oxocarboxylic acid metabolism
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000796
IPR004838
IPR004839
IPR015421
IPR015424