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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 3-oxo-5-beta-steroid 4-dehydrogenase

UniprotKB/SwissProt ID: AK1D1_MOUSE (Q8VCX1)

Gene Name: Akr1d1

Organism: Mus musculus (Mouse).

Function: Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7- alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4- cholesten-3-one can also act as substrates.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (By similarity).

Network with metabolic pathway:
Kegg map ID Pathway Link
map00120Primary bile acid biosynthesis
map00140Steroid hormone biosynthesis
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001395