UniprotKB/SwissProt ID: AKP13_HUMAN (Q12802)
Gene Name: AKAP13
Synonyms: BRX, HT31, LBC
Organism: Homo sapiens (Human).
Function: Anchors cAMP-dependent protein kinase (PKA) and acts as an adapter protein to selectively couple G alpha-13 and Rho. Augments gene activation by the estrogen receptor in an element- specific and ligand-dependent manner. Activates estrogen receptor beta by a p38 MAPK-dependent pathway. Stimulates exchange activity on Rho proteins in vitro, but not on CDC42, Ras or Rac and may bind calcium ions.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus. Membrane.
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PDB :
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