Protein Name: Sodium/potassium-transporting ATPase subunit alpha-1
|
UniprotKB/SwissProt ID: AT1A1_HUMAN (P05023)
Gene Name: ATP1A1
Organism: Homo sapiens (Human).
Function: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane; Multi-pass membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
| |
|
Protein disease:
|
| Disease database |
Database Entry |
Disease information | | OMIM | 182310 | ATPase, Na/K TRANSPORTING, ALPHA-1 POLYPEPTIDE; ATP1A1 ;;SODIUM-POTASSIUM-ATPase, ALPHA-1 |
|
Network with metabolic pathway:
|
|
Graphical Visualization of S-nitrosylation Sites:
|
| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
|
