UniprotKB/SwissProt ID: BASI_HUMAN (P35613)
Gene Name: BSG
Organism: Homo sapiens (Human).
Function: Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane; Single-pass type I membrane protein. Melanosome. Note=Colocalizes with SLC16A1 and SLC16A8 (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
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PDB :
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