Protein Name: Macrophage-capping protein
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UniprotKB/SwissProt ID: CAPG_MOUSE (P24452)
Gene Name: Capg
Synonyms: Mbh1
Organism: Mus musculus (Mouse).
Function: Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. Uncapping occurs either when Ca(2+) falls or when the concentration of polyphosphoinositide rises, both at low and high Ca(2+).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm. Secreted. Melanosome (By similarity). Note=Nuclear GCAP39 redistributes throughout the cytoplasm during mitosis and is excluded from regions containing chromosomes.
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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