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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Clathrin heavy chain 1

UniprotKB/SwissProt ID: CLH1_RAT (P11442)

Gene Name: Cltc

Organism: Rattus norvegicus (Rat).

Function: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Melanosome (By similarity). Note=Cytoplasmic face of coated pits and vesicles.

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
1BPO X-ray 2.60 A A/B/C1-494Link
1C9I X-ray 2.90 A A/B1-359Link
1C9L X-ray 2.90 A A/B3-359Link

The S-nitrosylation sites of CLH1_RAT

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1151MFDRHSSLAG C QIINYRTDAK   %RC0322178444-
2870PWLEARIHEG C EEPATHNALA   %RC0122178444-