Protein Name: Cytochrome c oxidase subunit 2
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UniprotKB/SwissProt ID: COX2_HUMAN (P00403)
Gene Name: MT-CO2
Synonyms: COII, COXII, MTCO2
Organism: Homo sapiens (Human).
Function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion inner membrane; Multi-pass membrane protein.
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | OMIM | 516040 | COMPLEX IV, CYTOCHROME c OXIDASE SUBUNIT II; MTCO2 ;;CYTOCHROME c OXIDASE II; COII | | OMIM | 540000 | MITOCHONDRIAL MYOPATHY, ENCEPHALOPATHY, LACTIC ACIDOSIS, AND STROKE-LIKE EPISODES; MELAS ; |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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