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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Sterol 26-hydroxylase, mitochondrial

UniprotKB/SwissProt ID: CP27A_MOUSE (Q9DBG1)

Gene Name: Cyp27a1

Organism: Mus musculus (Mouse).

Function: Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta- cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3- 25-hydroxylase activity (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion membrane (By similarity).

Network with metabolic pathway:
Kegg map ID Pathway Link
map00120Primary bile acid biosynthesis
map03320PPAR signaling pathway
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001128
IPR002401

The S-nitrosylation sites of CP27A_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1230TYILFEKRIG C LKPSIPEDTA HHHHHCCCCC C CCCCCCHHHH 4.03%MC0622178444-
2230TYILFEKRIG C LKPSIPEDTA HHHHHCCCCC C CCCCCCHHHH 4.03%MC0620837516in vivo