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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Cytochrome P450 2D10

UniprotKB/SwissProt ID: CP2DA_MOUSE (P24456)

Gene Name: Cyp2d10

Synonyms: Cyp2d-10

Organism: Mus musculus (Mouse).

Function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Network with metabolic pathway:
Kegg map ID Pathway Link
map00980Metabolism of xenobiotics by cytochrome P450
map00982Drug metabolism - cytochrome P450
map04726Serotonergic synapse
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001128
IPR002401
IPR008069

The S-nitrosylation sites of CP2DA_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1446FMPFSAGRRS C LGEPLARMEL EECCCCCCCC C HHHHHHHHHH 5.55%MC0522178444-
2446FMPFSAGRRS C LGEPLARMEL EECCCCCCCC C HHHHHHHHHH 5.55%MC0520837516in vivo