dbSNO 2.0

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Protein Name: Probable ATP-dependent RNA helicase DDX6

UniprotKB/SwissProt ID: DDX6_HUMAN (P26196)

Gene Name: DDX6

Synonyms: HLR2, RCK

Organism: Homo sapiens (Human).

Function: In the process of mRNA degradation, may play a role in mRNA decapping.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, P-body.

PDB :
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Network with metabolic pathway:

Kegg map ID	Pathway	Link
map03018	RNA degradation

Graphical Visualization of S-nitrosylation Sites:

Overview of Protein S-nitrosylation Sites with Functional and Structural Information

InterPro ID	Domain
IPR000629
IPR001650
IPR011545
IPR014001
IPR014014
IPR014021

3D Structure Databases:


3D structure databases
Entry	Method	Resolution (A)	Chain	Positions	View
1VEC	X-ray	2.01 A	A/B	94-299	Link
2WAX	X-ray	2.30 A	A/C	296-483	Link
2WAY	X-ray	2.30 A	A/C	296-483	Link

The S-nitrosylation sites of DDX6_HUMAN

No.	Position	S-nitrosylated Peptide	Secondary Structure of S-nitrosylated Peptide	Solvent Accessibility of nitrosylated Site	Substrate Motifs	PubMed ID	Experiment
1	324	AYVTERQKVH C LNTLFSRLQI	EEECCCCHHH H HHHHHHHHCC	3.34%	HC02	19483679	in vivo

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