UniprotKB/SwissProt ID: DECR2_MOUSE (Q9WV68)
Gene Name: Decr2
Synonyms: Pdcr
Organism: Mus musculus (Mouse).
Function: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19- docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Peroxisome.
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