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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Dihydropteridine reductase

UniprotKB/SwissProt ID: DHPR_MOUSE (Q8BVI4)

Gene Name: Qdpr

Synonyms: Dhpr

Organism: Mus musculus (Mouse).

Function: The product of this enzyme, tetrahydrobiopterin (BH-4), is an essential cofactor for phenylalanine, tyrosine, and tryptophan hydroxylases (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Network with metabolic pathway:
Kegg map ID Pathway Link
map00790Folate biosynthesis
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR002198

The S-nitrosylation sites of DHPR_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
182LGDQKVDAIL C VAGGWAGGNA HCCCCCCEEE E EECCCCCCCC 1.29%MC1321278135in vitro
2101NAKSKSLFKN C DMMWKQSMWT CCHHHHHHHH H HHHHHHHHHH 3.50%MC0421278135in vitro
3158GMAKGAVHQL C QSLAGKNSGM HHHHHHHHHH H HHHCCCCCCC 1.76%MC0122178444-
4158GMAKGAVHQL C QSLAGKNSGM HHHHHHHHHH H HHHCCCCCCC 1.76%MC0122588120-
5158GMAKGAVHQL C QSLAGKNSGM HHHHHHHHHH H HHHCCCCCCC 1.76%MC0121278135in vitro
6158GMAKGAVHQL C QSLAGKNSGM HHHHHHHHHH H HHHCCCCCCC 1.76%MC0120837516in vivo