Protein Name: Protein diaphanous homolog 2
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UniprotKB/SwissProt ID: DIAP2_HUMAN (O60879)
Gene Name: DIAPH2
Synonyms: DIA
Organism: Homo sapiens (Human).
Function: Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Isoform 3: Cytoplasm, cytosol. Early endosome. Note=Isoform 3 is cytosolic but when coexpressed with RHOD, the 2 proteins colocalize to early endosomes.
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | HPRD | 02117 | Premature ovarian failure 2A |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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