UniprotKB/SwissProt ID: DNJC3_MOUSE (Q91YW3)
Gene Name: Dnajc3
Synonyms: P58ipk
Organism: Mus musculus (Mouse).
Function: Involved in the unfolded protein response (UPR) during ER stress. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum.
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PDB :
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