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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Elongation factor Ts, mitochondrial

UniprotKB/SwissProt ID: EFTS_HUMAN (P43897)

Gene Name: TSFM

Organism: Homo sapiens (Human).

Function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion.

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Protein disease:
Disease database Database Entry Disease information
HPRD05285Combined oxidative phosphorylation deficiency 3
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000449
IPR001816
IPR009060
IPR014039

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
2CP9 NMR - A45-95Link

The S-nitrosylation sites of EFTS_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
171FVNCKKALET C GGDLKQAEIW HHHHHHHHHH C CCCHHHHHHH 4.13%HC1219483679in vivo
2240VLGKYGALVI C ETSEQKTNLE HCCEEEEEEE E ECCCCCCCHH 3.48%HC0119483679in vivo