Protein Name: EH domain-containing protein 2
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UniprotKB/SwissProt ID: EHD2_RAT (Q4V8H8)
Gene Name: Ehd2
Organism: Rattus norvegicus (Rat).
Function: Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Required for translocation of FER1L5 to the plasma membrane. Binds ATP; does not bind GTP (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein. Note=Colocalizes with FER1L5 at plasma membrane in myoblasts and myotubes (By similarity). Detected in intracellular vesicles, together with GLU
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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Overview of Protein S-nitrosylation Sites with Functional and Structural Information | |
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