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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Fatty acid-binding protein, adipocyte

UniprotKB/SwissProt ID: FABP4_MOUSE (P04117)

Gene Name: Fabp4

Synonyms: Ap2

Organism: Mus musculus (Mouse).

Function: Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map03320PPAR signaling pathway
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
1A18 X-ray 2.40 A A2-131Link
1A2D X-ray 2.40 A A/B2-131Link
1AB0 X-ray 1.90 A A3-131Link
1ACD X-ray 2.70 A A3-131Link
1ADL X-ray 1.60 A A2-132Link
1ALB X-ray 2.50 A A2-132Link
1G74 X-ray 1.70 A A2-132Link
1G7N X-ray 1.50 A A2-132Link
1LIB X-ray 1.70 A A2-132Link
1LIC X-ray 1.60 A A2-132Link
1LID X-ray 1.60 A A2-132Link
1LIE X-ray 1.60 A A2-132Link
1LIF X-ray 1.60 A A2-132Link
2ANS X-ray 2.50 A A/B2-132Link
2Q9S X-ray 2.30 A A1-132Link
2QM9 X-ray 2.31 A A/B1-132Link
3HK1 X-ray 1.70 A A2-132Link
3JS1 X-ray 1.81 A A/B2-132Link
3JSQ X-ray 2.30 A A2-132Link

The S-nitrosylation sites of FABP4_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
12---------M C DAFVGTWKLV ---------  5.34%MC1322865876in vivo
2118KRDGDKLVVE C VMKGVTSTRV   2.15%MC0324926564-
3118KRDGDKLVVE C VMKGVTSTRV   2.15%MC0321278135in vitro