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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Formimidoyltransferase-cyclodeaminase

UniprotKB/SwissProt ID: FTCD_MOUSE (Q91XD4)

Gene Name: Ftcd

Organism: Mus musculus (Mouse).

Function: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity). Binds and promotes bundling of vimentin filaments originating from the Golgi (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole (By similarity). Golgi apparatus (By similarity). Note=More abundantly located around the mother centriole (By similarity).

Network with metabolic pathway:
Kegg map ID Pathway Link
map00340Histidine metabolism
map00670One carbon pool by folate
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR004227
IPR007044
IPR012886
IPR013802

The S-nitrosylation sites of FTCD_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
157TVYTFVGQPE C VVEGALHAAR EEEEECCCHH H HHHHHHHHHH 5.45%MC0522178444-
257TVYTFVGQPE C VVEGALHAAR EEEEECCCHH H HHHHHHHHHH 5.45%MC0520837516
(Cys60)
in vivo
3438NTPEERDRRA C ALQEGLRQAV CCHHHHHHHH H HHHHHHHHHH 3.54%MC0522178444-
4438NTPEERDRRA C ALQEGLRQAV CCHHHHHHHH H HHHHHHHHHH 3.54%MC0520837516in vivo