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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Guanine nucleotide-binding protein subunit alpha-11

UniprotKB/SwissProt ID: GNA11_HUMAN (P29992)

Gene Name: GNA11

Synonyms: GA11

Organism: Homo sapiens (Human).

Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane; Lipid-anchor (Probable).

Protein disease:
Disease database Database Entry Disease information
OMIM139313GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-11; GNA11
OMIM145981HYPOCALCIURIC HYPERCALCEMIA, FAMILIAL, TYPE II; HHC2 ;;FAMILIAL BENIGN HYPERCALCEMIA, TYPE I
OMIM615361HYPOCALCEMIA, AUTOSOMAL DOMINANT 2; HYPOC2
Network with metabolic pathway:
Kegg map ID Pathway Link
map04540Gap junction
map04725Cholinergic synapse
map04730Long-term depression
map04912GnRH signaling pathway
map05142Chagas disease (American trypanosomiasis)
map05146Amoebiasis
map04020Calcium signaling pathway
map04270Vascular smooth muscle contraction
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000654
IPR001019
IPR011025