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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Glutathione S-transferase Mu 5

UniprotKB/SwissProt ID: GSTM5_MOUSE (P48774)

Gene Name: Gstm5

Synonyms: Fsc2, Gstm3

Organism: Mus musculus (Mouse).

Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.

Network with metabolic pathway:
Kegg map ID Pathway Link
map00480Glutathione metabolism
map00980Metabolism of xenobiotics by cytochrome P450
map00982Drug metabolism - cytochrome P450
map05204Chemical carcinogenesis
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR003081
IPR004045
IPR004046
IPR010987
IPR012335
IPR012336

The S-nitrosylation sites of GSTM5_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
138DTSYEEKRYI C GEAPDYDRSQ CCCEEHEEEE C CCCCCCCCHH 2.74%MC1021278135in vitro
290LRYIARKHNM C GDTEEEKIRV HHHHHHHCCC C CCCHHHHHHH 5.60%MC0321278135in vitro