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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Coproporphyrinogen-III oxidase, mitochondrial

UniprotKB/SwissProt ID: HEM6_MOUSE (P36552)

Gene Name: Cpox

Synonyms: Cpo

Organism: Mus musculus (Mouse).

Function: Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion intermembrane space.

Network with metabolic pathway:
Kegg map ID Pathway Link
map00860Porphyrin and chlorophyll metabolism
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001260

The S-nitrosylation sites of HEM6_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1308PDIYPKFKKW C DDYFFIVHRG CHHHHHHHHH C CCCCCCCCCC 3.81%MC0322865876in vivo
2362PSYVPIVKKH C DDSYTPRDKL CHHHHHHHHH C CCCCCHHHHH 9.50%MC0321278135in vitro
3362PSYVPIVKKH C DDSYTPRDKL CHHHHHHHHH C CCCCCHHHHH 9.50%MC0322865876in vivo