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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Heterogeneous nuclear ribonucleoprotein H

UniprotKB/SwissProt ID: HNRH1_MOUSE (O35737)

Gene Name: Hnrnph1

Synonyms: Hnrph, Hnrph1

Organism: Mus musculus (Mouse).

Function: This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG) (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus, nucleoplasm (By similarity).

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000504
IPR012677
IPR012996

The S-nitrosylation sites of HNRH1_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
122VVKVRGLPWS C SADEVQRFFS EEEEECCCCC C CHHHHHHHHH 3.25%MC0520925432in vivo
2290GSTFQSTTGH C VHMRGLPYRA CCCCCCCCCC E EEEECCCCCC 2.08%MC0320925432in vivo
3290GSTFQSTTGH C VHMRGLPYRA CCCCCCCCCC E EEEECCCCCC 2.08%MC0321278135in vitro