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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ig mu chain C region

UniprotKB/SwissProt ID: IGHM_MOUSE (P01872)

Gene Name: Ighm

Synonyms: Igh-6

Organism: Mus musculus (Mouse).

Function: IgM antibodies play an important role in primary defense mechanisms. They have been shown to be involved in early recognition of external invaders like bacteria and viruses, cellular waste and modified self, as well as in recognition and elimination of precancerous and cancerous lesions (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Isoform 1: Secreted (Probable). Note=During differentiation, B-lymphocytes switch from expression of membrane- bound IgM to secretion of IgM (Probable). Isoform 2: Cell membrane; Single-pass membrane protein (Potential).

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information