Protein Name: Integrin alpha-5
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UniprotKB/SwissProt ID: ITA5_HUMAN (P08648)
Gene Name: ITGA5
Synonyms: FNRA
Organism: Homo sapiens (Human).
Function: Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Membrane; Single-pass type I membrane protein.
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PDB :
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | OMIM | 135620 | INTEGRIN, ALPHA-5; ITGA5 ;;FIBRONECTIN RECEPTOR, ALPHA SUBUNIT; FNRA;; VERY LATE ACTIVATION |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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