Protein Name: Potassium voltage-gated channel subfamily C member 3
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UniprotKB/SwissProt ID: KCNC3_HUMAN (Q14003)
Gene Name: KCNC3
Organism: Homo sapiens (Human).
Function: This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Membrane; Multi-pass membrane protein.
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | KEGG | H00063 | Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3) | | OMIM | 176264 | POTASSIUM CHANNEL, VOLTAGE-GATED, SHAW-RELATED SUBFAMILY, MEMBER 3; KCNC3 | | OMIM | 605259 | SPINOCEREBELLAR ATAXIA 13; SCA13 | | HPRD | 08886 | Spinocerebellar ataxia 13 |
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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