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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: EKC/KEOPS complex subunit LAGE3

UniprotKB/SwissProt ID: LAGE3_HUMAN (Q14657)

Gene Name: LAGE3

Synonyms: DXS9879E, ESO3, ITBA2

Organism: Homo sapiens (Human).

Function: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus.

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR015419