UniprotKB/SwissProt ID: LARP7_HUMAN (Q4G0J3)
Gene Name: LARP7
Organism: Homo sapiens (Human).
Function: Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus, nucleoplasm.
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