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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: LIM and SH3 domain protein 1

UniprotKB/SwissProt ID: LASP1_MOUSE (Q61792)

Gene Name: Lasp1

Synonyms: Mln50

Organism: Mus musculus (Mouse).

Function: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cell cortex (By similarity). Cytoplasm, cytoskeleton (By similarity). Note=Associated with the F-actin rich cortical cytoskeleton (By similarity).

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000900
IPR001452
IPR001781
IPR013998

The S-nitrosylation sites of LASP1_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
153NYKGYEKKPY C NAHYPKQSFT CEEEECCEEE E CCCCHHHCCC 5.00%MC0221278135in vitro