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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: L-lactate dehydrogenase A chain

UniprotKB/SwissProt ID: LDHA_MOUSE (P06151)

Gene Name: Ldha

Synonyms: Ldh-1, Ldh1

Organism: Mus musculus (Mouse).

Function:

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.

Network with metabolic pathway:
Kegg map ID Pathway Link
map00010Glycolysis / Gluconeogenesis
map00270Cysteine and methionine metabolism
map00620Pyruvate metabolism
map00640Propanoate metabolism
map04066HIF-1 signaling pathway
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001236
IPR001557
IPR011304
IPR015955
The S-nitrosylation sites of LDHA_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
135VVGVGAVGMA C AISILMKDLA EECCCHHHHH H HHHHHHCCCC 2.28%MC0520837516in vivo
235VVGVGAVGMA C AISILMKDLA EECCCHHHHH H HHHHHHCCCC 2.28%MC0522865876in vivo
384TPKIVSSKDY C VTANSKLVII CCEEEECCCH H HHCCCCEEEE 2.92%MC0221278135in vitro
484TPKIVSSKDY C VTANSKLVII CCEEEECCCH H HHCCCCEEEE 2.92%MC0220837516in vivo
584TPKIVSSKDY C VTANSKLVII CCEEEECCCH H HHCCCCEEEE 2.92%MC0222865876in vivo
6131IPNIVKYSPH C KLLIVSNPVD HHHHHHHCCC E EEEEECCCHH 3.64%MC1322865876in vivo
7163FPKNRVIGSG C NLDSARFRYL CCHHHEEECC C HHHHHHHHHH 4.97%MC0224926564-
8163FPKNRVIGSG C NLDSARFRYL CCHHHEEECC C HHHHHHHHHH 4.97%MC0219101475-
9163FPKNRVIGSG C NLDSARFRYL CCHHHEEECC C HHHHHHHHHH 4.97%MC0221278135in vitro
10163FPKNRVIGSG C NLDSARFRYL CCHHHEEECC C HHHHHHHHHH 4.97%MC0220837516in vivo
11163FPKNRVIGSG C NLDSARFRYL CCHHHEEECC C HHHHHHHHHH 4.97%MC0222865876in vivo
12185GERLGVHALS C HGWVLGEHGD HHHHCCCHHH E EEEEEECCCC 3.42%MC1022865876in vivo
13293INEDVFLSVP C ILGQNGISDV CCCCCEEEEE E EECCCCEEEE 3.62%MC1321278135in vitro
14293INEDVFLSVP C ILGQNGISDV CCCCCEEEEE E EECCCCEEEE 3.62%MC1322865876in vivo