Protein Name: O-acetyl-ADP-ribose deacetylase MACROD1
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UniprotKB/SwissProt ID: MACD1_MOUSE (Q922B1)
Gene Name: Macrod1
Synonyms: Lrp16
Organism: Mus musculus (Mouse).
Function: Removes ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus (By similarity). Note=Recruited to DNA lesions, probably via mono-APD-ribosylated proteins (By similarity).
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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