Protein Name: Lysophospholipid acyltransferase 2
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UniprotKB/SwissProt ID: MBOA2_HUMAN (Q6ZWT7)
Gene Name: MBOAT2
Synonyms: OACT2
Organism: Homo sapiens (Human).
Function: Acyltransferase which mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn-glycero-3- phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2- diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity). Catalyzes also the acylation of lysophosphatidic acid (LPA) into phosphatidic acid (PA) (LPAAT activity). Has also a very weak lysophosphatidylcholine acyltransferase (LPCAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Membrane; Multi-pass membrane protein (Potential).
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | OMIM | 611949 | MEMBRANE-BOUND O-ACYLTRANSFERASE DOMAIN-CONTAINING 2; MBOAT2 ;;MEMBRANE-BOUND O-ACYLTRANSFER |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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