UniprotKB/SwissProt ID: MFN1_MOUSE (Q811U4)
Gene Name: Mfn1
Organism: Mus musculus (Mouse).
Function: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion outer membrane; Multi-pass membrane protein (By similarity).
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