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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Protein CBFA2T2

UniprotKB/SwissProt ID: MTG8R_HUMAN (O43439)

Gene Name: CBFA2T2

Synonyms: EHT, MTGR1

Organism: Homo sapiens (Human).

Function: May function as a complex with the chimeric protein RUNX1/AML1-CBFA2T1/MTG8 which is produced in acute myeloid leukemia with the chromosomal translocation t(8;21). May thus be involved in the repression of AML1-dependent transcription and the induction of G-CSF/CSF3-dependent cell growth. May be a tumor suppressor gene candidate involved in myeloid tumors with the deletion of the 20q11 region.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus (Probable).

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR002893
IPR003894
IPR013289
IPR013291
IPR014896