Protein Name: Protein CBFA2T2
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UniprotKB/SwissProt ID: MTG8R_HUMAN (O43439)
Gene Name: CBFA2T2
Synonyms: EHT, MTGR1
Organism: Homo sapiens (Human).
Function: May function as a complex with the chimeric protein RUNX1/AML1-CBFA2T1/MTG8 which is produced in acute myeloid leukemia with the chromosomal translocation t(8;21). May thus be involved in the repression of AML1-dependent transcription and the induction of G-CSF/CSF3-dependent cell growth. May be a tumor suppressor gene candidate involved in myeloid tumors with the deletion of the 20q11 region.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus (Probable).
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Graphical Visualization of S-nitrosylation Sites:
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Overview of Protein S-nitrosylation Sites with Functional and Structural Information | |
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