Protein Name: Myotubularin-related protein 2
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UniprotKB/SwissProt ID: MTMR2_HUMAN (Q13614)
Gene Name: MTMR2
Synonyms: KIAA1073
Organism: Homo sapiens (Human).
Function: Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Early endosome membrane; Peripheral membrane protein. Note=Partly associated with membranes.
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PDB :
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | KEGG | H00264 | Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atroph | | OMIM | 601382 | CHARCOT-MARIE-TOOTH DISEASE, TYPE 4B1; CMT4B1 ;;CHARCOT-MARIE-TOOTH DISEASE, AUTOSOMAL RECES | | OMIM | 603557 | MYOTUBULARIN-RELATED PROTEIN 2; MTMR2 ;;KIAA1073 | | HPRD | 04650 | Charcot-Marie-tooth disease, type 4b1 |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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