dbSNO 2.0

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Protein Name: Myosin light chain 3

UniprotKB/SwissProt ID: MYL3_MOUSE (P09542)

Gene Name: Myl3

Synonyms: Mlc1v, Mylc

Organism: Mus musculus (Mouse).

Function: Regulatory light chain of myosin. Does not bind calcium.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Network with metabolic pathway:

Kegg map ID	Pathway	Link
map04260	Cardiac muscle contraction
map05410	Hypertrophic cardiomyopathy (HCM)
map05414	Dilated cardiomyopathy

Graphical Visualization of S-nitrosylation Sites:

Overview of Protein S-nitrosylation Sites with Functional and Structural Information

InterPro ID	Domain
IPR002048
IPR011992

The S-nitrosylation sites of MYL3_MOUSE

No.	Position	S-nitrosylated Peptide	Secondary Structure of S-nitrosylated Peptide	Solvent Accessibility of nitrosylated Site	Substrate Motifs	PubMed ID	Experiment
1	85	KGEMKITYGQ C GDVLRALGQN	CCCEEECHHH H HHHHHHCCCC	4.34%	MC04	21278135	in vitro
2	85	KGEMKITYGQ C GDVLRALGQN	CCCEEECHHH H HHHHHHCCCC	4.34%	MC04	22865876	in vivo
3	191	LMAGQEDSNG C INYEAFVKHI	HHHHCCCCCC E ECHHHHHHHH	1.82%	MC03	21278135	in vitro
4	191	LMAGQEDSNG C INYEAFVKHI	HHHHCCCCCC E ECHHHHHHHH	1.82%	MC03	22865876	in vivo

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