logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Neutral cholesterol ester hydrolase 1

UniprotKB/SwissProt ID: NCEH1_MOUSE (Q8BLF1)

Gene Name: Nceh1

Synonyms: Aadacl1, Kiaa1363

Organism: Mus musculus (Mouse).

Function: Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane; Single-pass type II membrane protein (By similarity). Microsome.

Network with metabolic pathway:
Kegg map ID Pathway Link
map04976Bile secretion
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

The S-nitrosylation sites of NCEH1_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1345EALPKTYILT C EHDVLRDDGI   3.81%MC0222865876in vivo