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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

UniprotKB/SwissProt ID: NDUS7_MOUSE (Q9DC70)

Gene Name: Ndufs7

Organism: Mus musculus (Mouse).

Function: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion (By similarity).

Network with metabolic pathway:
Kegg map ID Pathway Link
map00190Oxidative phosphorylation
map05010Alzheimer's disease
map05012Parkinson's disease
map05016Huntington's disease
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR006137
IPR006138
IPR014406

The S-nitrosylation sites of NDUS7_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1164EPRYVVSMGS C ANGGGYYHYS CCCEEEEECH H HCCCCCCCCC 2.56%MC1321278135in vitro
2164EPRYVVSMGS C ANGGGYYHYS CCCEEEEECH H HCCCCCCCCC 2.56%MC1322865876in vivo
3194IVPVDIYVPG C PPTAEALLYG EEEEEEEECC C CCCHHHHHHH 2.74%MC1322865876in vivo