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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Neurofilament heavy polypeptide

UniprotKB/SwissProt ID: NFH_MOUSE (P19246)

Gene Name: Nefh

Synonyms: Kiaa0845, Nfh

Organism: Mus musculus (Mouse).

Function: Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Network with metabolic pathway:
Kegg map ID Pathway Link
map05014Amyotrophic lateral sclerosis (ALS)
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001664
IPR004829
IPR010790

The S-nitrosylation sites of NFH_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1225QKKAQALQEE C GYLRRHHQEE HHHHHHHHHH H HHHHHHHHHH 4.23%MC0222178444-
2225QKKAQALQEE C GYLRRHHQEE HHHHHHHHHH H HHHHHHHHHH 4.23%MC0222588120-
3225QKKAQALQEE C GYLRRHHQEE HHHHHHHHHH H HHHHHHHHHH 4.23%MC0219101475-
4263AQAEARDALK C DVTSALREIR EECHHCCCCC C CHHHHHHHHH 5.45%MC0522178444-
5263AQAEARDALK C DVTSALREIR EECHHCCCCC C CHHHHHHHHH 5.45%MC0519101475-