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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: ATP-dependent (S)-NAD(P)H-hydrate dehydratase

UniprotKB/SwissProt ID: NNRD_MOUSE (Q9CZ42)

Gene Name: Carkd

Organism: Mus musculus (Mouse).

Function: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion.

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

The S-nitrosylation sites of NNRD_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1306SPLLVAAWGA C TLTRECNRQA   2.56%MC0722865876in vivo