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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: NAD(P)H-hydrate epimerase

UniprotKB/SwissProt ID: NNRE_MOUSE (Q8K4Z3)

Gene Name: Apoa1bp

Synonyms: Aibp

Organism: Mus musculus (Mouse).

Function: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion (By similarity). Secreted. Note=In sperm, secretion gradually increases during capacitation.

PDB :
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Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
2DG2 X-ray 2.45 A A/B/C/D/E/F25-282Link
2O8N X-ray 2.00 A A25-282Link
3RNO X-ray 2.50 A A25-282Link
3RO7 X-ray 2.50 A A25-282Link
3ROE X-ray 2.11 A A/B/C/D/E/F25-282Link
3ROG X-ray 2.05 A A25-282Link
3ROX X-ray 2.40 A A25-282Link
3ROZ X-ray 2.80 A A25-282Link

The S-nitrosylation sites of NNRE_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1109SKSPPTVLVI C GPGNNGGDGL   4.14%MC0822865876in vivo
2121PGNNGGDGLV C ARHLKLFGYQ   3.11%MC0422865876in vivo
3152KPLFTGLVTQ C QKMDIPFLGE   2.83%MC0622865876in vivo
4277LNLPSYPDTE C VYRLQ-----   3.37%MC1222865876in vivo