UniprotKB/SwissProt ID: PAPD1_HUMAN (Q9NVV4)
Gene Name: MTPAP
Synonyms: PAPD1
Organism: Homo sapiens (Human).
Function: Polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. Can use all four nucleotides, but has higher activity with ATP and UTP (in vitro). Plays a role in replication-dependent histone mRNA degradation. May be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated. Might be responsible for the creation of some UAA stop codons which are not encoded in mtDNA.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Mitochondrion.
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PDB :
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