UniprotKB/SwissProt ID: PHC2_HUMAN (Q8IXK0)
Gene Name: PHC2
Synonyms: EDR2, PH2
Organism: Homo sapiens (Human).
Function: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.
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