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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Proteasome subunit beta type-7

UniprotKB/SwissProt ID: PSB7_MOUSE (P70195)

Gene Name: Psmb7

Synonyms: Mmc14

Organism: Mus musculus (Mouse).

Function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the trypsin-like activity of the proteasome (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus.

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map03050Proteasome
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000243
IPR001353

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
3UNB X-ray 2.90 A H/V/j/x44-277Link
3UNE X-ray 3.20 A H/V/j/x44-277Link

The S-nitrosylation sites of PSB7_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
174TEGMVVADKN C SKIHFISPNI CCCCEEECCC C CEEEEECCEE 5.59%MC0621278135in vitro