Protein Name: Transcriptional activator protein Pur-beta
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UniprotKB/SwissProt ID: PURB_HUMAN (Q96QR8)
Gene Name: PURB
Organism: Homo sapiens (Human).
Function: Has capacity to bind repeated elements in single- stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine- rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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